Devil May Cry 5 (DMC 5) - Mission 2 – Qliphoth Walkthrough

A complete walklthrough for Mission 2 - Qlipoth in Devil May Cry 5, including mission objectives, boss strategy guides, obtainable weapons, and orb locations.

Devil May Cry 5 - Mission 1 - Red Grave Alleyway

Mission 2 – Qliphoth Walkthrough

Story

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

Characters

Characters
Devil May Cry 5 - Nero IconNero Devil May Cry 5 - Nico IconNico
Devil May Cry 5 - V IconV

Obtainable Elements

Orbs

Item Location
Red Orbs Red Grave city square,  hotel, and alleyway
Blue Orb and Fragment Red Grave city hotel and alleyway

Devil Breakers

Location Devil Breaker
First Area Gerbera x1, Punch Line x1
Second Area Gerbera x1, Overture x1
Third Area Gerbera x1

Devil Breaker List

First Area: Red Grave City Square

1 Watch the cutscene: Morrison’s Letter.
2 Explore and Purchase Devil Breakers or Skills from Nico’s Shop.
3 Read the tutorial for “Devil Breaker,” “Breakage,” and “Breakaway”.
4 Proceed through the alleyway and run straight to the first city square.
5 Battle with Red Empusas in the first city square.
6 Proceed down the alleyway and acquire Red Orbs as you go.
7 Battle with Spiky Tentacles in the second city square.
8 Battle with “Cleaving Vanguard” Hell Cainas.
9 Read the tutorial for “Wire Snatch.”

Second Area: Red Grave Hotel

10 Enter the Red Grave city hotel.
11 Proceed to the second floor and look for Blue Orbs. Enter the open hallway on the right.
12 Watch the cutscene: V engaging in the battle below. Proceed to the second floor.
13 Read the tutorial for “Nidhogg Hatchling.” Use the hatchling on the blocking Qliphoth root.
14 Proceed to the third floor. Pick up the Red Orb.
15 Read the tutorial for “The Next Objective.” Battle with a Red Empusa.
16 Proceed to fourth floor. Battle with three Hell Cainas.
17 Look for another Nidhogg Hatchling while preparing for an ambush from two Hell Cainas. Place the hatchling on another Qliphoth root.
18 Read the tutorial for “Blue Orb Fragments.”
19 Proceed down the fifth floor hallway until you encounter a Qliphoth root. Enter the collapsed room on the right.
20 Read the tutorial for “Secret Mission.” Enter Secret Mission 1.
21 Secret Mission 1: Eliminate all of the demons (Red Empusas, Green Empusas, and Hell Cainas.)
22 Leave the room and proceed to the hotel dining area.
23 Battle with four Hell Cainas and one Green Empusa.
24 Leave the hotel by jumping from the dining area balcony.

Third Area: Red Grave City Alleyway and Church

25 Watch the cutscene: Qliphoth Tree in Red Grave city
26 Battle with Green Empusas.
27 Look for another Nidhogg Hatchling and place it on a blocking Qliphoth root.
28 Proceed to the alleyway. Pick up the Blue Orb
29 Battle with “Brutal Berserker” Hell Antenoras.
30 Watch the cutscene and read the tutorial for “Phone Booth.”
31 Enter the phonebooth and shop in Nico’s Shop.
32 Boss battle with Goliath.

Mission 2 – Qliphoth Walkthrough Strategy

4) Proceed down the alleyway and run straight to the first city square.

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

5) Battle with Red Empusas in the first city square

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

6) Proceed down the alleyway.

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

8) Battle with “Cleaving Vanguard” Hell Cainas

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

11) Proceed to the second floor and look for Blue Orbs. Enter the open hallway on the right

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

13) Read the tutorial for “Nidhogg Hatchling.” Place the hatchling on the blocking Qliphoth root.

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

14) Proceed to the third floor.

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

16) Proceed to the fourth floor. Battle with three Hell Cainas.

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

Check if a pile of Red Orbs is available in this room. It is only available in certain difficulty settings.

17) Look for another Nidhogg Hatchling while preparing for an ambush from two Hell Cainas. Place the hatchling on another Qliphoth root

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

18) Read the tutorial for “Blue Orb Fragments.” Pick up the Blue Orb Fragment

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

19) Proceed down the fifth floor hallway until you encounter a Qliphoth root. Enter the collapsed area on the right

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

You will be able to access Secret Mission 1 once you enter the collapsed room.

23) Battle with four Hell Cainas and one Green Empusa

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

27) Look for another Nidhogg Hatchling and place it on a blocking Qliphoth root

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

28) Proceed down the alleyway. Pick-up Blue Orb

Devil May Cry 5 - Mission 2 - Qlipoth Walkthrough

30)  Enter the phonebooth and shop in Nico’s Shop

DMC 5 Demo Walkthrough

After proceeding down the blocked path, you will find a Phone Booth that lets you manage your equipment. It is possible to skip this and go straight to the boss fight, but it is best to make a short stop to prepare for the upcoming battle.

32) Boss battle with Goliath commences

Devil May Cry 5 - Mission 1 - Goliath Boss

Goliath Boss Strategy Guide

Goliath is encountered at the end of Mission 2. Though not that fast, Goliath hits hard and has a variety of attacks playerse need to avoid. Try to get behind it to avoid its swings. Many of Goliath’s close-range attacks can be dodged, especially if you go airborne. Gerbera is a good choice for the fight, as it allows you to quickly move out of harm’s way. Green Orbs can be found scattered around the third area of the boss fight to help you get through the battle.

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