Nioh and Nioh 2 (including all DLCs) are also bundled in the Nioh Collection on PS5.
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Nue Boss Guide
Her boss battle begins with William pushing open an immense set of double doors and entering into a courtyard. A bolt of lightning strikes the ground, and Nue appears.
Nue may appear as if she’s giving up her back to you, but don’t be fooled. Her fur is covered in electricity, damaging you if you get too excited. She also whips her tail around, serving as her ranged attack. In addition, she can call on lightning bolts to target William during the battle, so it’s best to keep a respectful distance from her. At the other end, Nue can produce a beam of electricity or poison from her mouth, as well as pounce on you with her claws.
To beat Nue, equip a spear and select Low Stance. Do a dodge to the LEFT of her head when she breathes electricity or poison. There is a little blind spot there that won’t be reached by her attack. Don’t bother taking cover from the trees or other structures in her area, as her beams will just pass through them and hit you.
Notice her glowing underside? When Nue pounces at you, try to dodge. She will land on her side, exposing her underside. Get in close to land a few hits which will deal extra damage to her health. She won’t stay down for long, though. Call on a Guardian Spirit if you need an extra boost in offense against this monster. Continue on with these tactics to end the battle off for good.